merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1944,Anti-Collagen Type VI Antibody, clone 3C4

  • merck millipore,默克密理博,MAB1944,Anti-Collagen Type VI Antibody, clone 3C4

    产品名称：Anti-Collagen Type VI Antibody, clone 3C4
    产品型号：MAB1944
    This Anti-Collagen Type VI Antibody, clone 3C4 is validated for use in IC, IH for the detection of Collagen Type VI.

    merck millipore,默克密理博,MAB1944,Anti-Collagen Type VI Antibody, clone 3C4

  • 产品介绍
  • merck millipore,默克密理博,MAB1944,Anti-Collagen Type VI Antibody, clone 3C4

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, ICCMAscitesMonoclonal Antibody
    描述
    产品目录编号 MAB1944
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Collagen Type VI Antibody, clone 3C4
    产品信息
    格式 Ascites
    演示 Liquid
    应用
    应用 This Anti-Collagen Type VI Antibody, clone 3C4 is validated for use in IC, IH for the detection of Collagen Type VI.
    主要应用
    • Immunohistochemistry
    • Immunocytochemistry
    应用说明 Immunohistochemistry (see reference). Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified human collagen VI
    克隆 3C4
    宿主 Mouse
    特异性 Reacts with human collagen VI (other species not tested).
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001848.2
    Entrez基因汇总 The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
    基因符号
    • OPLL
    • COL6A1
    UniProt编号
    • P12109
    UniProt汇总 FUNCTION: SwissProt: P12109 # Collagen VI acts as a cell-binding protein.
    SIZE: 1028 amino acids; 108529 Da
    SUBUNIT: Trimers composed of three different chains: alpha 1(VI), alpha 2(VI), and alpha 3(VI).
    SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix (By similarity).
    PTM: Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
    DISEASE: SwissProt: P12109 # Defects in COL6A1 are a cause of Bethlem myopathy (BM) [MIM:158810]. BM is a rare autosomal dominant proximal myopathy characterized by early childhood onset (complete penetrance by the age of 5) and joint contractures most frequently affecting the elbows and ankles.
    SIMILARITY: SwissProt: P12109 ## Contains 3 VWFA domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain frozen at -20°C. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MAB1944,Anti-Collagen Type VI Antibody, clone 3C4

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下一件merck millipore产品：merck millipore,默克密理博,PP1239-K,IgG Hybridoma Blend, Augmented (1mg)


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