merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1387Z,Anti-CD11b Antibody, clone M1/70.15.1, azide free

  • merck millipore,默克密理博,MAB1387Z,Anti-CD11b Antibody, clone M1/70.15.1, azide free

    产品名称：Anti-CD11b Antibody, clone M1/70.15.1, azide free
    产品型号：MAB1387Z
    Anti-CD11b Antibody, clone M1/70.15.1, azide free is an antibody against CD11b for use in FC, IF, IH & IP.

    merck millipore,默克密理博,MAB1387Z,Anti-CD11b Antibody, clone M1/70.15.1, azide free

  • 产品介绍
  • merck millipore,默克密理博,MAB1387Z,Anti-CD11b Antibody, clone M1/70.15.1, azide free

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HIHC, FCRPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1387Z
    Replaces MAB88919
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-CD11b Antibody, clone M1/70.15.1, azide free
    Alternate Names
    • Mac-1a
    • MAB1387
    • Integrin alpha M
    产品信息
    格式 Purified
    控制
    • Spleen, Cerebellum (Microglia)
    演示 Purified rat immunoglobulin in PBS containing no preservatives
    应用
    应用 Anti-CD11b Antibody, clone M1/70.15.1, azide free is an antibody against CD11b for use in FC, IF, IH & IP.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    不建议的应用
    • Immunohistochemistry (Paraffin)
    应用说明 Flow Cytometry 1:50-1:100

    Immunohistology on fresh frozen or acetone fixed tissues.

    Immunohistochemistry on paraffin embedded tissues fixed in PLP, methyl-carnoy, or 2% PFA; traditional 10% formalin fixation is problematic.

    Immunoprecipitation: use a rabbit anti-rat capture antibody rather than protein G or A.

    Functional/blocking of C3bi binding to its receptor.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 T cell enriched splenocytes from B10 mice
    克隆 M1/70.15.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rat
    特异性 Recognizes the murine alphaM integrin chain, which exists as a heterodimer with the beta2 integrin (Springer, 1979; Springer, 1990). The antibody stains polymorphonuclear cells, monocytes and NK cells. Variable activity is reported with tissue macrophages. M1/70.15.1 blocks iC3b binding to its receptor (Beller, 1982).
    同种型 IgG2b
    品种反应性 MouseHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000632.3
    Entrez基因汇总 This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Some integrin alpha M proteins contain an inserted amino acid (Q, between AA positions 499 and 500) resulting from a 3bp shift in a splice acceptor that inserts the codon CAG; receptors with or without the extra amino acid are functionally indistinguishable
    基因符号
    • MGC117044
    • ITGAM
    • MO1A
    • CD11b
    • MAC1A
    • CD11B
    • MAC-1
    • CR3A
    纯化方法 Protein G purfied
    UniProt编号
    • P11215
    UniProt汇总 FUNCTION: SwissProt: P11215 # Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
    SIZE: 1152 amino acids; 127179 Da
    SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Predominantly expressed in monocytes and granulocytes.
    DOMAIN: SwissProt: P11215 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1387Z,Anti-CD11b Antibody, clone M1/70.15.1, azide free

上一件merck millipore产品：merck millipore,默克密理博,AB5612,Anti-Citrulline Antibody
下一件merck millipore产品：merck millipore,默克密理博,SF-1528,CCR5; Human, Cyanine 5 RNA Detection Probe,SmartFlare


相关产品

merck millipore,默克密理博,346299,D(+)Glucosamine, Hydrochloride - CAS 66-84-2 - Calbiochem merck millipore,默克密理博,346299,D(+)Glucosamine, Hydrochloride - CAS 66-84-2 - Calbiochem

merck millipore,默克密理博,SF-802,PDPK1; Human, Cyanine 3 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-802,PDPK1; Human, Cyanine 3 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,SCR531,STEMCCA Cre-Excisable Constitutive Polycistronic (OKSM) Lentivirus Reprogramming Kit merck millipore,默克密理博,SCR531,STEMCCA Cre-Excisable Constitutive Polycistronic (OKSM) Lentivirus Reprogr...

merck millipore,默克密理博,MAB13442,Anti-MMP-13 Antibody, clone 181-14G11 merck millipore,默克密理博,MAB13442,Anti-MMP-13 Antibody, clone 181-14G11

merck millipore,默克密理博,AB5612,Anti-Citrulline Antibody merck millipore,默克密理博,AB5612,Anti-Citrulline Antibody

merck millipore,默克密理博,SF-1528,CCR5; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1528,CCR5; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,PF024,MMP-9, Active, Human, Recombinant merck millipore,默克密理博,PF024,MMP-9, Active, Human, Recombinant

merck millipore,默克密理博,LSKMAGT02,PureProteome™ Streptavidin Magnetic Bead System merck millipore,默克密理博,LSKMAGT02,PureProteome™ Streptavidin Magnetic Bead System

merck millipore,默克密理博,SF-1007,Desmin; Human, Cyanine 5, RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1007,Desmin; Human, Cyanine 5, RNA Detection Probe,SmartFlare

merck millipore,默克密理博,405268,Indomethacin - CAS 53-86-1 - Calbiochem merck millipore,默克密理博,405268,Indomethacin - CAS 53-86-1 - Calbiochem


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部