merck millipore,默克密理愽
  • merck millipore,默克密理博,IHCR2110-6,IHC Select Anti-CD4 Antibody, prediluted, clone 4B12

  • merck millipore,默克密理博,IHCR2110-6,IHC Select Anti-CD4 Antibody, prediluted, clone 4B12

    产品名称：IHC Select Anti-CD4 Antibody, prediluted, clone 4B12
    产品型号：IHCR2110-6
    This IHC Select Anti-CD4 Antibody, prediluted, clone 4B12 is validated for use in IH(P) for the detection of CD4.

    merck millipore,默克密理博,IHCR2110-6,IHC Select Anti-CD4 Antibody, prediluted, clone 4B12

  • 产品介绍
  • merck millipore,默克密理博,IHCR2110-6,IHC Select Anti-CD4 Antibody, prediluted, clone 4B12

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIH(P)MPurifiedMonoclonal Antibody
    描述
    产品目录编号 IHCR2110-6
    商名
    • Chemicon
    • IHC Select
    描述 IHC Select® Anti-CD4 Antibody, prediluted, clone 4B12
    产品信息
    格式 Purified
    演示 Liquid diluted in PBS, pH 7.2 with stabilizers, 0.2% Tween 20, and 0.1% ProClin 300 as preservative.
    应用
    应用 This IHC Select Anti-CD4 Antibody, prediluted, clone 4B12 is validated for use in IH(P) for the detection of CD4.
    主要应用
    • Immunohistochemistry (Paraffin)
    应用说明 Antibody is prediluted and ready to use for Immunohistochemistry of formalin-fixed, paraffin-embedded tissues.

    Pretreatment: Heat Induced Epitope Retrieval (HIER). Recommend EDTA, pH 8.0 (Cat. No. 21546). No signal was detected without Epitope retrieval.

    Incubation: 10 minutes with IHC Select® Detection Kits.

    CD4 has been prediluted for use as the primary antibody with Chemicon's IHC Select® Detection Kits and Protocols (Catalog Nos. DAB050, DET-HP1000, APR050, and DET-APR1000), but other supplier's IHC detection systems may be used.
    生物信息
    免疫原品种 Prokaryotic recombinant protein corresponding to the external domain of the CD4 molecule/Mouse myeloma.
    克隆 4B12
    宿主 Mouse
    特异性 The CD4 molecule (T4) is a single chain transmembrane glycoprotein with a molecular weight of 59kDa. The CD4 antigen is found on a T cell subset known as helper/inducer representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes, and at a lower level on monocytes. CD4 is expressed in the majority of T-cell lymphomas, including mycosis fungoides. HTLV-1 associated adult T cell leukemia/lymphoma is also generally CD4 positive. A typical lymphoma CD4 panel includes CD3, CD5, CD8, CD7 and TIA-1.
    同种型 IgG1κ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000616.3
    基因符号
    • CD4mut
    • CD4
    UniProt编号
    • P01730
    UniProt汇总 FUNCTION: SwissProt: P01730 # Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
    SIZE: 458 amino acids; 51111 Da
    SUBUNIT: Associates with LCK. Binds to HIV-1 gp120 and to P4HB/PDI and upon HIV-1 binding to the cell membrane, is part of P4HB/PDI- CD4-CXCR4-gp120 complex. Interacts with HIV-1 Envelope polyprotein gp160 and protein Vpu.
    SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
    PTM: Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
    SIMILARITY: SwissProt: P01730 ## Contains 3 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    MISCELLANEOUS: Primary receptor for HIV-1.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C . Refer to vial for expiration dating.
    包装信息
    数量 6 mL

    merck millipore,默克密理博,IHCR2110-6,IHC Select Anti-CD4 Antibody, prediluted, clone 4B12

上一件merck millipore产品：merck millipore,默克密理博,AB9220,Anti-Nanog Antibody
下一件merck millipore产品：merck millipore,默克密理博,EZHPYYT66K,Human PYY (Total) ELISA


相关产品

merck millipore,默克密理博,400011,Caspase-1 Inhibitor I, Cell-Permeable - Calbiochem merck millipore,默克密理博,400011,Caspase-1 Inhibitor I, Cell-Permeable - Calbiochem

merck millipore,默克密理博,CBL1512,Anti-Integrin αM [CD11b] Antibody, clone OX-42 merck millipore,默克密理博,CBL1512,Anti-Integrin αM [CD11b] Antibody, clone OX-42

merck millipore,默克密理博,ABE223-S,Anti-acetyl Histone H3 (Lys4) Antibody, Trial Size merck millipore,默克密理博,ABE223-S,Anti-acetyl Histone H3 (Lys4) Antibody, Trial Size

merck millipore,默克密理博,539175,Proteasome Inhibitor IV - Calbiochem merck millipore,默克密理博,539175,Proteasome Inhibitor IV - Calbiochem

merck millipore,默克密理博,AB9220,Anti-Nanog Antibody merck millipore,默克密理博,AB9220,Anti-Nanog Antibody

merck millipore,默克密理博,EZHPYYT66K,Human PYY (Total) ELISA merck millipore,默克密理博,EZHPYYT66K,Human PYY (Total) ELISA

merck millipore,默克密理博,14-632,TSSK2 Protein, active, 10 µg merck millipore,默克密理博,14-632,TSSK2 Protein, active, 10 µg

merck millipore,默克密理博,AP503,Goat Anti-Mouse IgG γ chain Antibody, Species Adsorbed merck millipore,默克密理博,AP503,Goat Anti-Mouse IgG γ chain Antibody, Species Adsorbed

merck millipore,默克密理博,1951,Bacitracin - CAS 1405-87-4 - Calbiochem merck millipore,默克密理博,1951,Bacitracin - CAS 1405-87-4 - Calbiochem

merck millipore,默克密理博,480275,β-NGF, Human, Recombinant, NSO Cells merck millipore,默克密理博,480275,β-NGF, Human, Recombinant, NSO Cells


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部