merck millipore,默克密理博,IHCR1006-6,Anti-Nestin Antibody, prediluted, clone rat-401

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, M	IH(P)	M	Purified	Monoclonal Antibody

描述
产品目录编号	IHCR1006-6
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-Nestin Antibody, prediluted, clone rat-401
概述	Nestin is a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells (Mokry and Nemecek, 1998).. Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GMBs (Glioblastoma multiformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinomas.

产品信息
格式	Purified
演示	Liquid diluted in PBS, pH 7.2 with stabilizers, 0.2% Tween 20, and 0.1% ProClin 300 as preservative.

应用
应用	Anti-Nestin Antibody, prediluted, clone rat-401 detects level of Nestin & has been published & validated for use in IH(P).
主要应用	Immunohistochemistry (Paraffin)

生物信息
免疫原品种	Nestin purified from embryonic rat spinal cord.
克隆	rat-401
宿主	Mouse
特异性	Rodent Nestin protein confirmed with rat and mouse. Rat-401 is not reactive with human nestin protein.
同种型	IgG1
品种反应性	RatMouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_006617.1
Entrez基因汇总	Nestin is an intermediate filament protein that was first identified with a monoclonal antibody by Hockfield and McKay (1985) [PubMed 4078630]. It is expressed predominantly in stem cells of the central nervous system in the neural tube. Upon terminal neural differentiation, nestin is downregulated and replaced by neurofilaments.[supplied by OMIM]
基因符号	Nbla00170 NES ORFNames=Nbla00170 FLJ21841 Nestin.
非反应性品种	Human
UniProt编号	P48681
UniProt汇总	FUNCTION: SwissProt: P48681 # May play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daughter cells during progenitor cell division (By similarity). SIZE: 1621 amino acids; 177439 Da SUBUNIT: Interacts with FHOD3 (By similarity). TISSUE SPECIFICITY: CNS stem cells. DEVELOPMENTAL STAGE: Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments. SIMILARITY: SwissProt: P48681 ## Belongs to the intermediate filament family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at 2-8°C. Refer to vial for expiration dating.

包装信息
数量	6 mL

merck millipore,默克密理博,IHCR1006-6,Anti-Nestin Antibody, prediluted, clone rat-401

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech