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merck millipore,默克密理博,HKI3MAG-99K,MILLIPLEX MAP Human Kidney Injury Magnetic Bead Panel 3 - Toxicity Multiplex Assay
产品名称：MILLIPLEX MAP Human Kidney Injury Magnetic Bead Panel 3 - Toxicity Multiplex Assay
产品型号：HKI3MAG-99K
The analytes available for this multiplex kit are: β-2-Microglobulin (β2M), Retinol Binding Protein 4 (RBP4), Uromodulin.
merck millipore,默克密理博,HKI3MAG-99K,MILLIPLEX MAP Human Kidney Injury Magnetic Bead Panel 3 - Toxicity Multiplex Assay
- 产品介绍
- merck millipore,默克密理博,HKI3MAG-99K,MILLIPLEX MAP Human Kidney Injury Magnetic Bead Panel 3 - Toxicity Multiplex Assay
重要规格表
可用的分析物 品种反应性 主要应用 检测方法 Uromodulin, β-2-Microglobulin, RBP4 H Mplex Luminex xMAP 描述 产品目录编号 HKI3MAG-99K 商名 - MILLIPLEX
描述 MILLIPLEX MAP Human Kidney Injury Magnetic Bead Panel 3 - Toxicity Multiplex Assay 背景信息 Maintenance of physiological balance in the body is attributed in part to normal kidney function. Altered kidney function due to injury, drug toxicity or kidney failure may be life threatening. Toxicity is the leading cause of drug failure, so research is expanding in search of more sensitive, rapid methods to determine organ-specific damage as quickly as possible. Traditionally, blood urea nitrogen (BUN) and serum creatinine tests have been used to determine drug-induced damage to the kidney. These tests only detect kidney damage after it begins and do not allow for the elucidation of where in the kidney the damage has occurred. Specificity and earlier detection of kidney injury is vital, and this area of research is expanding in search of more sensitive, rapid methods for determining the specific area of damage in kidney.
EMD Millipore provides valuable research assays to investigate multiple biomarkers of kidney injury in human urine samples using the Luminex xMAP® instrument platform.产品信息 检测方法 Luminex xMAP 配置 Design your multiplex kit by choosing analytes. 精度（%） - Intra-assay: < 10%
- Inter-assay: < 15%
板面类型 MAGNETIC Toxicity 应用 应用 The analytes available for this multiplex kit are: β-2-Microglobulin (β2M), Retinol Binding Protein 4 (RBP4), Uromodulin. 主要应用 - Multiplexing
应用说明 • Customers need to determine the optimal dilution factor for their samples. Our recommendations are based on urine samples from normal subjects.
• These assays require 25 µL diluted urine sample per well, sample dilution recommendations is 1:500 dilution in kit Assay Buffer
• An overnight (4°C) incubation is recommended.生物信息 品种反应性 Human 可用的分析物 - Uromodulin
- β-2-Microglobulin
- RBP4
交叉反应性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel. 准确度 - 100% - 103%
理化信息 灵敏度 - Please see kit protocol for individual assay sensitivities.
- 0.052 - 0.175 ng/mL (MinDC = 2SD)
标准曲线范围 - Uromodulin: 0.10 – 100 ng/mL
- β-2-Microglobulin: 0.10 – 100 ng/mL
- RBP4: 0.05 – 50 ng/mL
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well plate
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