• merck millipore,默克密理博,GF121,Insulin-like Growth Factor-I Protein, Recombinant mouse
  • merck millipore,默克密理博,GF121,Insulin-like Growth Factor-I Protein, Recombinant mouse

    产品名称:Insulin-like Growth Factor-I Protein, Recombinant mouse
    产品型号:GF121
    Insulin Like Growth Factor-I (IGF-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone & cartilage tissue.

    merck millipore,默克密理博,GF121,Insulin-like Growth Factor-I Protein, Recombinant mouse

  • 产品介绍
  • merck millipore,默克密理博,GF121,Insulin-like Growth Factor-I Protein, Recombinant mouse

    重要规格表

    主要应用 品种 来源 纯度
    CULTMouseMouse, expressed in E.coliGreater than 97% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of IGF-I.
    描述
    产品目录编号 GF121
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Insulin-like Growth Factor-I Protein, Recombinant mouse
    概述 Insulin Like Growth Factor-I (IGF-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. Recombinant Mouse IGF-I is a 7.6 kDa protein containing 70 amino acid residues.
    Alternate Names
    • IGF-I
    产品信息
    演示 The sterile filtered solution was lyophilized with no additives.
    应用
    应用 Insulin Like Growth Factor-I (IGF-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone & cartilage tissue.
    主要应用
    • Cell Culture
    生物信息
    纯度 Greater than 97% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of IGF-I.
    来源 Mouse, expressed in E.coli
    品种 Mouse
    特异活性 The ED50 as determined using FDC-P1 cells is less than <2.0 ng/mL, corresponding to a specific activity of > 5 x 10E5 units/mg.
    Entrez基因汇总 The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972 [PubMed 4550398]). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986 [PubMed 3455760]; Rosenfeld, 2003 [PubMed 14657423]).[supplied by OMIM]
    基因符号
    • MGF
    • IGF1A
    • IGF1
    • IBP1
    UniProt编号
    • P05017
    • P05019
    UniProt汇总 FUNCTION: SwissProt: P05019 # The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.| P01343 # The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.
    SIZE: 195 amino acids; 21841 Da
    SUBCELLULAR LOCATION: Secreted.
    DOMAIN: SwissProt: P05019
    DISEASE: SwissProt: P05019 # Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.| P01343 # Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
    SIMILARITY: SwissProt: P05019 ## Belongs to the insulin family.| P01343 ## Belongs to the insulin family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Reconstituted mouse IGF-I should be stored in undiluted aliquots at -20°C. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,GF121,Insulin-like Growth Factor-I Protein, Recombinant mouse

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