merck millipore,默克密理博,FCMAB337F,Milli-Mark™ Anti-Myelin Associated Glycoprotein-FITC Antibody, clone 513

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R	FC	M	FITC	Monoclonal Antibody

描述
产品目录编号	FCMAB337F
商名	Milli-Mark
描述	Milli-Mark™ Anti-Myelin Associated Glycoprotein-FITC Antibody, clone 513
Alternate Names	MAG Brain neuron cytoplasmic protein 3 Sialic acid-binding Ig-like lectin 4a Siglec-4a
背景信息	Myelin-associated glycoprotein (MAG), a member of the immunoglobulin superfamily, is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin; Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.

产品信息
格式	FITC
控制	B35 cells
演示	Purified mouse monoclonal IgG1 conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA

应用
应用	This Milli-Mark Anti-Myelin Associated Glycoprotein-FITC Antibody, clone 513 is validated for use in FC for the detection of Myelin Associated Glycoprotein.
主要应用	Flow Cytometry

生物信息
免疫原品种	L2 epitope carrying glycoprotein extract of 1-2 old day chicken brain.
克隆	513
宿主	Mouse
特异性	Antibody recognizes Myelin Associated Glycoprotein.
同种型	IgG1
品种反应性	Rat
Species Reactivity Note	Tested and passed on Rat.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_058886
Entrez基因汇总	The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
基因符号	GMA MAG SIGLEC4A SIGLEC-4A Siglec-4a S-MAG
纯化方法	Protein A Purified
UniProt编号	P07722
UniProt汇总	FUNCTION: SwissProt: P20916 # Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha2,3- linked sialic acid (By similarity). SIZE: 626 amino acids; 69069 Da SUBUNIT: Binds to RTN4R (By similarity). SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: SwissProt: P20916 ## Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. & Contains 4 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 Ig-like V-type (immunoglobulin-like) domain.

产品使用声明
质量保证	Evaluated by flow cytometry using B35 cells
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB337F,Milli-Mark™ Anti-Myelin Associated Glycoprotein-FITC Antibody, clone 513

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