merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL579,Anti-CD81 Antibody, clone I.3.3.22

  • merck millipore,默克密理博,CBL579,Anti-CD81 Antibody, clone I.3.3.22

    产品名称：Anti-CD81 Antibody, clone I.3.3.22
    产品型号：CBL579
    This Anti-CD81 Antibody, clone I.3.3.22 is validated for use in FC, IP, FUNC for the detection of CD81.

    merck millipore,默克密理博,CBL579,Anti-CD81 Antibody, clone I.3.3.22

  • 产品介绍
  • merck millipore,默克密理博,CBL579,Anti-CD81 Antibody, clone I.3.3.22

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 CBL579
    Replaces CBL579P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-CD81 Antibody, clone I.3.3.22
    Alternate Names
    • TAPA-1
    产品信息
    格式 Purified
    演示 The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
    应用
    应用 This Anti-CD81 Antibody, clone I.3.3.22 is validated for use in FC, IP, FUNC for the detection of CD81.
    主要应用
    • Flow Cytometry
    应用说明 Flow cytometry

    Immunoprecipitation

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 B cell line derived from Burkitt lymphoma
    克隆 I.3.3.22
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 The antibody reacts with the human CD81 (TAPA-1) a 24kDa member of the TM4 super family of proteins with four transmembrane domains. The antibody has been shown to have anti-proliferative effects on different lymphoid cell lines particularly those of large cell lymphoma derivation.

    FUSION PARTNER: NS1 myeloma cells
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_004356.3
    Entrez基因汇总 The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies.
    基因符号
    • TSPAN28
    • CD81
    • S5.7
    • Tspan-28
    • TAPA1
    • TAPA-1
    • Tetraspanin-28
    UniProt编号
    • P60033
    UniProt汇总 FUNCTION: SwissProt: P60033 # May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May acts a the viral receptor for HCV.
    SIZE: 236 amino acids; 25809 Da
    SUBUNIT: Plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer. Interacts directly with IGSF8.
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
    PTM: Not glycosylated (Probable).
    SIMILARITY: SwissProt: P60033 ## Belongs to the tetraspanin (TM4SF) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,CBL579,Anti-CD81 Antibody, clone I.3.3.22

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