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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT165 描述 Anti-RAB8A Antibody Alternate Names - Oncogene c-mel
- Ras-related protein Rab-8A
背景信息 Ras-related protein Rab-8A (RAB8A) is one of two Rab8 isoforms, which belong to the superfamily of GTPases. They cycle between an active GTP-bound state, formed from interaction with guanine nucleotide exchange factors (GEFs) such as Rabin8 and GRAB; and an inactive GDP-bound state via interaction with GTPase activating proteins (GAPs) such as TBC1D1. Rab8A activates various effector molecules, which are coupled to intracellular signaling networks that mediate membrane and vesicular trafficking, and actin remodeling. Rab8A is found in the golgi network, perinuclear region, plasma membrane, lamellipodia, and cilia, among other regions. 产品信息 格式 Affinity Purified 控制 - Serum starved HeLa cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-RAB8A Antibody is validated for use in Western Blotting for the detection of RAB8A. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A representative lot from an independent laboratory detected RAB8A in human cerebellum and brain. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human RAB8A. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the C-terminus of RAB8A. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse and Bovine based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005361
基因符号 - RAB8
- RAB8A
- MEL
纯化方法 Affinity purified UniProt编号 - P61006
产品使用声明 质量保证 Evaluated by Western Blot in serum starved HeLa cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected RAB8A in serum starved HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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