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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT114 描述 Anti-LPA receptor 5 Antibody (GPR92) Alternate Names - G-protein coupled receptor 93
- Lysophosphatidic acid receptor 5
- LPA receptor 5
- LPA-5
- G-protein coupled receptor 92
背景信息 Lysophosphatidic acid receptor 5 (LPA receptor 5), also known as GPR92, is a G12/13 and Gq coupled receptor that mediates the signaling of LPA. Ligand binding to LPA receptor 5 may increase intracellular levels of cAMP and calcium, resulting in the activation of a wide range of effector molecules. Recent studies have demonstrated that LPA receptor 5 is abundantly expressed in human mast cells, and mediates the release of the macrophage inflammatory protein-1β (MIP-1β), indicating that LPA receptor 5 may play a role in innate and adaptive immunity. 产品信息 格式 Affinity Purified 控制 - K562 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the LPA receptor 5 protein using this Anti-LPA receptor 5 (GPR92) validated for use in WB. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A representative lot detected LPA receptor 5 in non-transfected CHEM-1 cells and CHEM-1 cells transfected with LPAR5(GPR92) (Catalogue. No. HTS209C - Transfected Cell Line).
Immunocychemistry Analysis: A 1:500 dilution from a representative lot detected LPAR5 in TF1 cells, non-transfected CHEM-1 cells and CHEM-1 cells transfected with LPAR5(GPR92) (Catalogue. No. HTS209C - Transfected Cell Line).
NOTE: The protein used to make the transfected CHEM1 cell line is full length LPAR5.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the extracellular domain of human LPA receptor 5. 表位 Extracellular domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the extracellular domain of LPA receptor 5. 品种反应性 MouseHuman Species Reactivity Note Demonstrated to react with Human and Mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_065133
基因符号 - GPR93
- LPAR5
- GPR92
纯化方法 Affinity purified UniProt编号 - Q9H1C0
产品使用声明 质量保证 Evaluated by Western Blot in K562 cell lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected LPA receptor 5 on 10 µg of K562 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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