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  • merck millipore,默克密理博,ABT113,Anti-LPA receptor 3 (Edg-7) Antibody

  • merck millipore,默克密理博,ABT113,Anti-LPA receptor 3 (Edg-7) Antibody

    产品名称：Anti-LPA receptor 3 (Edg-7) Antibody
    产品型号：ABT113
    Detect LPA receptor 3 (Edg-7) using this Anti-LPA receptor 3 (Edg-7) Antibody validated for use in Western Blotting, IHC(P).

    merck millipore,默克密理博,ABT113,Anti-LPA receptor 3 (Edg-7) Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABT113,Anti-LPA receptor 3 (Edg-7) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABT113
    描述 Anti-LPA receptor 3 (Edg-7) Antibody
    Alternate Names
    • Lysophosphatidic Acid Receptor Edg-7
    • Lysophosphatidic Acid Receptor 3
    • Lpa Receptor 3
    • Lpa-3
    背景信息 Lysophosphatidic acid receptor 3 (LPA receptor 3), also known as Edg-7, is a G-protein coupled receptor that interacts with Gi and Gq proteins and activates the MAP kinase pathway. It is highly expressed in the prostate, pancreas, testes, heart, ovary, and lung. The LPA receptor mediates a number of cellular processes such as growth, apoptosis, cell migration, and cytoskeleton changes.
    产品信息
    格式 Affinity Purified
    控制
    • Pc3 Cell Lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect LPA receptor 3 (Edg-7) using this Anti-LPA receptor 3 (Edg-7) Antibody validated for use in Western Blotting, IHC(P).
    主要应用
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:500-1,000 dilution from a representative lot detected LPA receptor 3 in human prostatic glandular epithelium tissue.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to the extracellular domain of human LPA receptor 3.
    表位 Extracellular domain
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes LPA receptor 3 at the extracellular domain.
    品种反应性 RatHuman
    Species Reactivity Note Demonstrated to react with Human and Rat. Other homologies: Mouse (83% sequence homology).
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • Np_036284
    Entrez基因汇总 This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008].
    基因符号
    • Lpa3
    • Lpar3
    • Edg7
    纯化方法 Affinity purified
    UniProt编号
    • Q9Uby5
    UniProt汇总 FUNCTION: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.

    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

    TISSUE SPECIFICITY: Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.

    SEQUENCE SIMLARITIES: Belongs to the G-protein coupled receptor 1 family.
    产品使用声明
    质量保证 Evaluated by Western Blot in PC3 cell lysate.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected LPA receptor 3 on 10 µg of PC3 cell lysate. Western Blot performed without Tween
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABT113,Anti-LPA receptor 3 (Edg-7) Antibody

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