merck millipore,默克密理博,ABE635,Anti-ETV4 Antibody

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merck millipore,默克密理博,ABE635,Anti-ETV4 Antibody
产品名称：Anti-ETV4 Antibody
产品型号：ABE635
Detect ETS translocation variant 4 protein using this rabbit polyclonal antibody, Anti-ETV4 Antibody validated for use in western blotting & IHC.

merck millipore,默克密理博,ABE635,Anti-ETV4 Antibody

产品介绍

merck millipore,默克密理博,ABE635,Anti-ETV4 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H, M	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABE635
描述	Anti-ETV4 Antibody
Alternate Names	ETV4 ETS translocation variant 4 Adenovirus E1A enhancer-binding protein E1A-F Polyomavirus enhancer activator 3 homolog Protein PEA3
背景信息	ETS translocation variant 4 protein (ETV4), alternatively known as Adenovirus E1A enhancer-binding protein E1A-F, or Polyomavirus enhancer activator 3 homolog (PEA3), is encoded by the human gene named ETVA/E1AF/PEA3. ETV4 is a protein that is a transcriptional activator that was first recognized as such because it allowed for the expression of the adenovirus E1A gene upon infection. Today ETV4 has been shown to be active in a wide variety of biological processes from stem cell differentiation, to mammary gland and duct morphogenesis to motor neuron and axon guidance. ETV4 activity is regulated via the ERK/MAP signaling and a complex interplay of post-translation modifications such as sumoylation and ubiquitination. In cancers, ETV4 activates HIF and its subsequent proliferation genes and overexpression in prostate cells leads to oncogenesis. EMD-Millipore’s Anti-ETV4 rabbit polyclonal antibody has been tested in western blot against mouse heart lysates and in paraffin embedded immunohistochemistry on human ovarian tumor tissue sections.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Detect ETS translocation variant 4 protein using this rabbit polyclonal antibody, Anti-ETV4 Antibody validated for use in western blotting & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ETV4 in human ovary tumor tissue.

生物信息
免疫原品种	GST-tagged fusion protein corresponding to human ETV4.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	HumanMouse
抗体类型	Polyclonal Antibody
基因符号	PEA3 ETV4 E1AF
纯化方法	Antigen Affinity purified
UniProt编号	P43268

产品使用声明
质量保证	Evaluated by Western Blotting in mouse heart tissue lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected ETV4 in mouse heart tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.