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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE490 描述 Anti-NSD2 Antibody Alternate Names - WHSC1
- Nuclear SET domain-containing protein 2, NSD2, Histone-lysine N-methyltransferase NSD2, Multiple myeloma SET domain-containing protein, MMSET, Protein trithorax-5 and Wolf-Hirschhorn syndrome candidate 1 protein, WHSC1, histone methyltransferase, Histone H3 'Lys-27', H3K27me, RE-IIBP, transcription regulator, HADC recruitment, DNA, suppress IL5 transcription, chromosomal aberrations, multiple myeloma tumors, Histone-lysine N-methyltransferase NSD2
- Multiple myeloma SET domain-containing protein
- MMSET
- Nuclear SET domain-containing protein 2
- Protein trithorax-5
- Wolf-Hirschhorn syndrome candidate 1 protein
背景信息 Nuclear SET domain-containing protein 2 (NSD2) is also called Histone-lysine N-methyltransferase NSD2, Multiple myeloma SET domain-containing protein (MMSET), Protein trithorax-5 and Wolf-Hirschhorn syndrome candidate 1 protein (WHSC1). NSD2 is a histone methyltransferase that acts on histone H3 'Lys-27' (H3K27me). Isoform RE-IIBP is thought to be a transcription regulator that uses HADC recruitment to binding DNA and suppress IL5 transcription. Chromosomal aberrations to WHSC1 are linked to multiple myeloma tumors. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect NSD using this rabbit polyclonal antibody, Anti-NSD2 Antibody validated for use in western blotting, IHC & IP. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected NSD2 in human cerebellum and thalamus tissues.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected NSD2 in human kidney tissues.
Immunoprecipitation Analysis: 5 µg of this antibody immunoprecipitated NSD2 from 500 µg of HCT-116 cell lysate.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to a region near the C-terminus of human NSD2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody is expected to cross-react with isoforms 1 (152 kDa), 3 (71 kDa), and 4 (66 kDa, REII-BP; IL-5 promoter REII-region-binding protein) based upon immunogen design. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001035889.1
基因符号 - TRX5
- WHSC1
- MMSET
- NSD2
纯化方法 Affinity purified UniProt编号 - O96028
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected NSD2 in 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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