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品种反应性 主要应用 宿主 格式 抗体类型 Chp, H, M, R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE315 描述 Anti-SMYD3 Antibody Alternate Names - SMYD3
- SET and MYND domain-containing protein 3
- Zinc finger MYND domain-containing protein 1
背景信息 SET and MYND domain-containing protein 3 (SMYD3), also known as Zinc finger MYND domain-containing protein 1 (ZMYND1), is a histone methyltransferase that methylates histone H3 at Lys4 leading to dimethylation and trimethylation. Its activity is strongly stimulated by HSPCA. SMYD3 also acts as a member of an RNA polymerase complex and plays an important role in transcriptional activation. SMYD3 is expressed in skeletal muscles and testis, and is also overexpressed in a majority of colorectal and hepatocellular carcinomas. 产品信息 格式 Affinity Purified 控制 - HCT116 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the SMYD3 protein using this Anti-SMYD3 validated for use in IHC. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected SMYD3 in human colorectal adenocarcinoma.
Western Blot Analysis: 0.5 µg/mL from a representative lot detected SMYD3 in 10 µg untransfected and SMYD3-transfected HEK293 cell lysates.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human SMYD3. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 ChimpanzeeHumanMouseRat Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse, Rat, and Chimpanzee based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001161212
基因符号 - ZNFN3A1
- SMYD3
- ZMYND1
纯化方法 Affinity purified UniProt编号 - Q9H7B4
产品使用声明 质量保证 Evaluated by Western Blot in HCT116 cell lysate.
Western Blot Analysis: 1.0 µg/mL of this antibody detected SMYD3 in 10 µg of HCT116 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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