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品种反应性 主要应用 宿主 格式 抗体类型 R, M WB Rb Serum Polyclonal Antibody 描述 产品目录编号 ABE1043 描述 Anti-CAVIN-3/PRKCDBP Antibody Alternate Names - Serum deprivation response factor-related gene product that binds to C-kinase
- Cavin-3
- Protein kinase C delta-binding protein
背景信息 CAVIN-3/PRKCDBP, also known as Cavin-3/SRBC or Serum deprivation response factor-related gene product that binds to C-kinase, and encoded by the gene Prkcdbp/Srbc, is an adapter molecule that binds PKCdelta and is a member of the STICK (substrates that interact with C-kinase) superfamily of PKC-binding proteins. CAVIN-3 binds caveolin and localizes to the caveolae. CAVIN-3 remains associated with caveolin when caveolae bud to form vesicles (cavicles) that travel on microtubules to different regions of the cell. In the absence of CAVIN-3 intracellular cavicle traffic is markedly impaired. CAVIN-3 is also called SRBC for (sdr-related gene product that binds to c-kinase). Caveolae are a major membrane domain common to most cells. One of the defining features of this domain is the protein caveolin, and it is now know that CAVIN-3 is critical to caveolae function. CAVIN-3 is expressed in uterus, ovary, mammary and epithelial cells. Also expressed in brain, lung, heart, spleen, intestine, kidney, skeletal muscle and testis, but it is not found in liver. The protein appears to be up-regulated in serum starved conditions and growth arrest conditions suggesting a survival response. 产品信息 格式 Serum 演示 Rabbit polyclonal serum containing 0.05% sodium azide. 应用 应用 Anti-CAVIN-3/PRKCDBP Antibody is a rabbit polyclonal antibody, validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to mouse CAVIN-3/PRKCDBP. 宿主 Rabbit 品种反应性 RatMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_082720
基因符号 - Srbc
- Prkcdbp
纯化方法 Unpurified UniProt编号 - Q91VJ2
产品使用声明 质量保证 Evaluated by Western Blotting in NIH/3T3 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected CAVIN-3/PRKCDBP in 10 µg of NIH/3T3 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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