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merck millipore,默克密理博,ABC234,Anti-phospho MLKL Antibody (Thr357)
产品名称:Anti-phospho MLKL Antibody (Thr357)
产品型号:ABC234
Detect Mixed lineage kinase domain-like protein using this rabbit polyclonal antibody, Anti-phospho MLKL Antibody (Thr357) validated for use in western blotting & Peptide Inhibition Assay.
merck millipore,默克密理博,ABC234,Anti-phospho MLKL Antibody (Thr357)
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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC234 描述 Anti-phospho MLKL Antibody (Thr357) Alternate Names - Mixed lineage kinase domain-like protein
背景信息 Mixed lineage kinase domain-like protein (MLKL) is involved in TNF-alpha induced apoptosis. It contains a pseudokinase domain that is catalytically inactive and an N-terminal domain. MLKL is phosphorylated by receptor-interacting serine-threonine kinase 3 (RIP3) that induces a conformational change leading to its homo-oligomerization, activation, and translocation to plasma membrane. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Mixed lineage kinase domain-like protein using this rabbit polyclonal antibody, Anti-phospho MLKL Antibody (Thr357) validated for use in western blotting & Peptide Inhibition Assay. 主要应用 - Western Blotting
应用说明 Western Blotting/Peptide Inhibition Analysis: 0.5 µg/mL from a representative lot blocked phospho MLKL (Thr357) in HT-29 cell lysate treated with cyclohexamide, Z-VAD-FMK, and TNFalpha. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the Protein Kinase domain of human MLKL phosphorylated at Thr357. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_689862
基因符号 - MLKL
纯化方法 Affinity purified UniProt编号 - Q8NB16
产品使用声明 质量保证 Evaluated by Western Blotting in HT-29 cell lysates, which were untreated or treated with cyclohexamide, Z-VAD-FMK, and TNFalpha.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected phospho MLKL (Thr357) in HT-29 cell lysate treated with cyclohexamide, Z-VAD-FMK, and TNFalpha.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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