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品种反应性 主要应用 宿主 格式 抗体类型 H IH(P) Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB9480 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Retinoic Acid-Induced 3 Antibody Alternate Names - RAI3/RAIG1
产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide. 应用 应用 Detect Retinoic Acid-Induced 3 using this Anti-Retinoic Acid-Induced 3 Antibody validated for use in IH(P). 主要应用 - Immunohistochemistry (Paraffin)
应用说明 Immunohistochemistry on paraffin embedded tissue sections.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from the 2nd extracellular domain of human Retinoic Acid-Induced 3. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Retinoic Acid-Induced 3 [RAI3/RAIG1]. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003979.3
Entrez基因汇总 This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. 基因符号 - GPCR5A
- GPRC5A
- RAIG-1
- RAIG1
- RAI3
UniProt编号 - Q8NFJ5
UniProt汇总 FUNCTION: SwissProt: Q8NFJ5 # Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
SIZE: 357 amino acids; 40251 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.
TISSUE SPECIFICITY: Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to Ref.5: expressed at low but detectable level in pancreas and heart.
SIMILARITY: SwissProt: Q8NFJ5 ## Belongs to the G-protein coupled receptor 3 family.产品使用声明 销售限制 This product is not available for sale in Japan. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µg
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