merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5087,Anti-Melanocyte Stimulating Hormone α Antibody

  • merck millipore,默克密理博,AB5087,Anti-Melanocyte Stimulating Hormone α Antibody

    产品名称：Anti-Melanocyte Stimulating Hormone α Antibody
    产品型号：AB5087
    Anti-Melanocyte Stimulating Hormone Antibody, α detects level of Melanocyte Stimulating Hormone & has been published & validated for use in IH, RIA.

    merck millipore,默克密理博,AB5087,Anti-Melanocyte Stimulating Hormone α Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5087,Anti-Melanocyte Stimulating Hormone α Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MaIHCShSerumPolyclonal Antibody
    描述
    产品目录编号 AB5087
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Melanocyte Stimulating Hormone α Antibody
    Alternate Names
    • Corticotropin-lipotropin precursor
    • alpha-MSH
    • POMC
    • Pro-opiomelanocortin
    产品信息
    格式 Serum
    控制
    • Hypothalamus
    演示 Sheep Serum. Liquid. Contains no preservative.
    应用
    应用 Anti-Melanocyte Stimulating Hormone Antibody, α detects level of Melanocyte Stimulating Hormone & has been published & validated for use in IH, RIA.
    主要应用
    • Immunohistochemistry
    应用说明 Immunohistochemistry: 1:10,000-1:50,000 on 4% paraformaldehyde fixed tissue.

    RIA: 1:250,000-1:300,000.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 MSH conjugated with bovine thyroglobulin.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Sheep
    特异性 Specific for alpha-melanocyte stimulating hormone (aMSH), C-terminal.
    品种反应性 Mammals
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001035256.1
    • NM_000939.2
    Entrez基因汇总 This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
    基因符号
    • CLIP
    • POMC
    • LPH
    • NPP
    • POC
    • ACTH
    纯化方法 Unpurified
    UniProt编号
    • P01189
    UniProt汇总 FUNCTION: MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.
    SIZE: 267 amino acids; 29424 Da
    TISSUE SPECIFICITY: Melanocytes and corticoadrenal tissue. Produced by the pituitary gland.
    SIMILARITY: Belongs to the POMC family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB5087,Anti-Melanocyte Stimulating Hormone α Antibody

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