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品种反应性 主要应用 宿主 格式 抗体类型 R, M IHC, WB Gp Serum Polyclonal Antibody 描述 产品目录编号 AB2251 Replaces AB5907 描述 Anti-VGLUT2 Antibody Alternate Names - vesicular glutamate transporter 2
- Differentiation-associated BNPI
- Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter
- Solute carrier family 17 member 6
- differentiation-associated Na-dependent inorganic phosphate cotransporter
- solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
- member 6
背景信息 VGLUT2 is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity. 产品信息 格式 Serum 控制 - Rat Brain Lysate
演示 GST-Depleted Sera; with 0.05% NaN3 应用 应用 This Anti-VGLUT2 Antibody is validated for use in WB, IH for the detection of VGLUT2. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry:
Tested on mouse floating brain sections at 1:12,000.生物信息 免疫原品种 Peptide corresponding to the C-terminal of rat VGLUT-2. 宿主 Guinea Pig 特异性 Cat. # AB2251 recognizes VGLUT2 品种反应性 RatMouse Species Reactivity Note Tested on mouse and rat. Sequence homology 100% with rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_020346.1
基因符号 - VGluT2
- DNPI
- VGLUT2
纯化方法 GST Depletion UniProt编号 - Q9JI12
UniProt汇总 FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
LOCATION: Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membraneBy similarity. Membrane; Multi-pass membrane proteinPotential. Cell junction › synapse › synaptosomeBy similarity.
SPECIFICITY:Predominantly expressed in adult brain. Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, puteman, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus.
Developmental stage Expressed in fetal brain.
SIMILARITY:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily
产品使用声明 质量保证 Routinely evaluated by western blot on rat brain lysate. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C.
包装信息 数量 50 µL
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