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merck millipore,默克密理博,AB10546,Anti-Bcl-2-associated transcription factor 1 Antibody
产品名称：Anti-Bcl-2-associated transcription factor 1 Antibody
产品型号：AB10546
This Anti-Bcl-2-associated transcription factor 1 Antibody is validated for use in WB, IP, IH(P) for the detection of Bcl-2-associated transcription factor 1.
merck millipore,默克密理博,AB10546,Anti-Bcl-2-associated transcription factor 1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Ca, H, M, B WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB10546 描述 Anti-Bcl-2-associated transcription factor 1 Antibody Alternate Names - bcl-2-associated transcription factor 1
- BCL2-associated transcription factor 1
背景信息 Bcl-2-associated transcription factor 1 (Btf) is a ubiquitously expressed death-promoting transcriptional repressor. It has been shown to interact with anti-apoptotic proteins related to Bcl-2, DNA, adenovirus E1B 19K, and EMD. Btf has also been shown to be involved in E1A transformation of p53 or E1B 19K, an interaction that implicates Btf as being involved in transcriptional regulation and in promoting apoptosis. Expression of Btf is absent in some cancers, which may suggest a potential role for the protein in tumor suppression. 产品信息 格式 Affinity Purified 控制 - HeLa cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Bcl-2-associated transcription factor 1 Antibody is validated for use in WB, IP, IH(P) for the detection of Bcl-2-associated transcription factor 1. 主要应用 - Western Blotting
应用说明 Western Blot (Snap i.d.) Analysis: 0.5 µg/mL from a previous lot detected Bcl-2-associated transcription factor 1 in 10 µg of HeLa cell lysate.
Immunoprecipitation Analysis: 10 µg of this antibody immunoprecipitated Bcl-2-associated transcription factor 1 from HeLa cell lysate.
Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Bcl-2-associated transcription factor 1 in neuronal and glial cells in normal human brain tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Bcl-2-associated transcription factor 1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 CanineHumanMouseBovine Species Reactivity Note Demonstrated to react with human and mouse.
Predicted to react with bovine and canine based on 100% sequence homology.
Other homologies: Rat (81% sequence homology).抗体类型 Polyclonal Antibody Entrez基因编号 - NP_055554
Entrez基因汇总 This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. 基因符号 - Btf
- BCLAF1
- BTF
纯化方法 Affinity Purified UniProt编号 - Q9NYF8
UniProt汇总 FUNCTION: Death-promoting transcriptional repressor.
SUBUNIT STRUCTURE: Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
TISSUE SPECIFICTY: Ubiquitous.
SEQUENCE CAUTION: The sequence AAH47687.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
The sequence AAH47887.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
The sequence AAH56894.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
The sequence AAH63846.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
The sequence BAA11481.2 differs from that shown. Reason: Erroneous initiation.产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Bcl-2-associated transcription factor 1 in 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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