merck millipore,默克密理愽
  • merck millipore,默克密理博,681629,W-7, Hydrochloride - CAS 61714-27-0 - Calbiochem

  • merck millipore,默克密理博,681629,W-7, Hydrochloride - CAS 61714-27-0 - Calbiochem

    产品名称：W-7, Hydrochloride - CAS 61714-27-0 - Calbiochem
    产品型号：681629
    A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC₅₀ = 51 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC₅₀ = 28 µM).

    merck millipore,默克密理博,681629,W-7, Hydrochloride - CAS 61714-27-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681629,W-7, Hydrochloride - CAS 61714-27-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₂₁ClN₂O₂S · HCl61714-27-0
    描述
    概述 A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 51 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 µM).
    产品目录编号 681629
    品牌系列 Calbiochem®
    同义词 N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide, HCl
    参考
    参考 Caulfield, M.P., et al. 1991. Neurosci. Lett. 125, 57.
    Asano, M. 1989. J. Pharmacol. Exp. Ther. 251, 764.
    Itoh, H., and Hidaka, H. 1984. J. Biochem. 96, 1721.
    Tanaka, T., et al. 1983. Pharmacol. 26, 249.
    Hidaka, H. 1981. Proc. Natl. Acad. Sci. USA 78, 4354.
    产品信息
    CAS号 61714-27-0
    具有ATP竞争性 N
    形式 Off-white crystalline solid
    Hill配方 C₁₆H₂₁ClN₂O₂S · HCl
    化学配方 C₁₆H₂₁ClN₂O₂S · HCl
    Molar Mass 377.4
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 Myosin light chain kinase
    主靶IC50 51 µM inhibiting myosin light chain kinase; 28 µM inhibiting Ca2+-calmodulin-dependent phosphodiesterase
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO, DMF, Warm EtOH
    GHS安全信息
    RTECS QK0786000
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

    merck millipore,默克密理博,681629,W-7, Hydrochloride - CAS 61714-27-0 - Calbiochem

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