merck millipore,默克密理愽
  • merck millipore,默克密理博,575310,T0901317 - CAS 293754-55-9 - Calbiochem

  • merck millipore,默克密理博,575310,T0901317 - CAS 293754-55-9 - Calbiochem

    产品名称：T0901317 - CAS 293754-55-9 - Calbiochem
    产品型号：575310
    A cell-permeable, nonsterol, benzenesulfonamide compound that acts as a highly selective and potent liver X receptor agonist (EC₅₀ of 20 nM for LXRα).

    merck millipore,默克密理博,575310,T0901317 - CAS 293754-55-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,575310,T0901317 - CAS 293754-55-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₁₂NSO₃F₉293754-55-9
    描述
    概述 A cell-permeable, nonsterol, benzenesulfonamide compound that acts as a highly selective and potent liver X receptor agonist (EC50 of 20 nM for LXRα). Reported to induce the expression of genes associated with fatty acid biosynthesis and raise both the levels of serum HDL cholesterol and triglyceride in mice. Also reduces the development of atherosclerosis in LDL receptor-deficient mice and lowers plasma glucose in diabetic rodents.
    产品目录编号 575310
    品牌系列 Calbiochem®
    同义词 TO-901317, N-(2,2,2-Trifluoroethyl)-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]sulfonamide
    参考
    参考 Terasaka, N., et al. 2003. FEBS Lett. 536, 6.
    Cao, G., et al. 2002. J. Biol. Chem. 278, 1131.
    Field, F.J., et al. 2002. Biochem. J. 368, 855.
    Fukumoto, H., et al. 2002. J. Biol. Chem. 277, 48508.
    DeBose-Boyd, R.A., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 1477.
    Repa, J.J., et al. 2000. Science 289, 1524.
    Schultz, J.R., et al. 2000. Genes Dev. 14, 2831.
    产品信息
    CAS号 293754-55-9
    具有ATP竞争性 N
    形式 Light beige solid
    Hill配方 C₁₇H₁₂NSO₃F₉
    化学配方 C₁₇H₁₂NSO₃F₉
    Molar Mass 481.3
    可逆 N
    结构配方图像
    生物信息
    主靶 Liver X receptor (LXRα)
    主靶IC50 EC50 = 20 nM for LXRα
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Harmful
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,575310,T0901317 - CAS 293754-55-9 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,48-660MAG,MILLIPLEX MAP MAPK/SAPK Signaling 10-Plex Kit - Cell Signaling Multiplex Assay


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