merck millipore,默克密理愽
  • merck millipore,默克密理博,574715,Syk Inhibitor V - Calbiochem

  • merck millipore,默克密理博,574715,Syk Inhibitor V - Calbiochem

    产品名称：Syk Inhibitor V - Calbiochem
    产品型号：574715
    The Syk Inhibitor V controls the biological activity of Syk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,574715,Syk Inhibitor V - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,574715,Syk Inhibitor V - Calbiochem

    重要规格表

    经验配方
    C₂₀H₂₃N₅O₂S
    描述
    概述 A cell-permeable 4-thiazolyl-2-phenylaminopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of spleen tyrosine kinase (Syk) (Ki = 9nM). Exhibits excellent selectivity over Cdk2 (Ki >= 3.33 µM); ROCK (Ki = 2.3 µM), Src (Ki >= 3.33 µM) and ZAP 70 (Ki = 240 nM). Shown to inhibit mast cell degranulation (IC50 = 70 nM) that is commonly observed in asthma and other allergic diseases.
    产品目录编号 574715
    品牌系列 Calbiochem®
    同义词 (S)-2-(2-((3,5-dimethylphenyl)amino)pyrimidin-4-yl)-N-(1-hydroxypropan-2-yl)-4-methylthiazole-5-carboxamide, Spleen Tyrosine Kinase Inhibitor
    参考
    参考 Farmer, L., et al. 2008. Bioorg. Med. Chem. Lett. 18, 6231.
    产品信息
    形式 Yellow solid
    Hill配方 C₂₀H₂₃N₅O₂S
    化学配方 C₂₀H₂₃N₅O₂S
    Molar Mass 397.5
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°c.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,574715,Syk Inhibitor V - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,ABN301,Anti-HCCS Antibody
下一件merck millipore产品：merck millipore,默克密理博,506126,p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem


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