merck millipore,默克密理愽
  • merck millipore,默克密理博,565730,Scriptaid - CAS 287383-59-9 - Calbiochem

  • merck millipore,默克密理博,565730,Scriptaid - CAS 287383-59-9 - Calbiochem

    产品名称：Scriptaid - CAS 287383-59-9 - Calbiochem
    产品型号：565730
    A relatively non-toxic, cell-permeable hydroxamic acid-containing histone deacetylase (HDAC) inhibitor.

    merck millipore,默克密理博,565730,Scriptaid - CAS 287383-59-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,565730,Scriptaid - CAS 287383-59-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₁₈N₂O₄287383-59-9
    描述
    概述 A relatively non-toxic, cell-permeable hydroxamic acid-containing histone deacetylase (HDAC) inhibitor. Facilitates transcriptional activation (TGFβ/Smad4) in both stable and transient receptor assays in a concentration-dependent manner. At ~2 µg/ml (6-8 µM) concentrations, results in a greater than 100-fold increase in histone acetylation in PANC-1 cells. Reported to derepress hTERT by inhibiting the recruitment of HDAC into E2F-pocket protein complexes assembled on the hTERT promoter.
    产品目录编号 565730
    品牌系列 Calbiochem®
    同义词 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexanoic Acid Hydroxyamide, CGK1026, HDAC Inhibitor XIII
    参考
    参考 Won, J., et al. 2004. Proc. Natl. Acad. Sci. USA 101, 11328.
    Su, G.H., et al. 2000. Cancer Res. 60, 3137.
    产品信息
    CAS号 287383-59-9
    具有ATP竞争性 N
    声明 Sold under license of U.S. Patent 6,544,957.
    形式 Off-white Solid
    Hill配方 C₁₈H₁₈N₂O₄
    化学配方 C₁₈H₁₈N₂O₄
    Molar Mass 326.4
    可逆 N
    结构配方图像
    生物信息
    主靶 HDAC
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,565730,Scriptaid - CAS 287383-59-9 - Calbiochem

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