merck millipore,默克密理愽
  • merck millipore,默克密理博,528282,Polo-like Kinase Inhibitor I

  • merck millipore,默克密理博,528282,Polo-like Kinase Inhibitor I

    产品名称：Polo-like Kinase Inhibitor I
    产品型号：528282
    The Polo-like Kinase Inhibitor I, also referenced under CAS 916985-21-2, controls the biological activity of Polo-like Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dep More>>

    merck millipore,默克密理博,528282,Polo-like Kinase Inhibitor I

  • 产品介绍
  • merck millipore,默克密理博,528282,Polo-like Kinase Inhibitor I

    重要规格表

    经验配方 CAS号
    C₂₂H₂₁N₃O₆S₂916985-21-2
    描述
    概述 A thiophenecarboxamide compound that acts as a potent and ATP-binding site-targeting inhibitor of polo-like kinase 1 (IC50 = 126 nM) with excellent selectivity over IKK-2 and IKK-3 (IC50 > 16 µM).
    产品目录编号 528282
    品牌系列 Calbiochem®
    同义词 5-(5,6-Dimethoxybenzimidazol-1-yl)-3-(4-methanesulfonyl-benzyloxy)-thiophene-2-carboxamide, Plk Inhibitor I
    参考
    参考 Bamborough, P., et al. 2006. Bioorg. Med. Chem. Lett. 16, 6236.
    产品信息
    CAS号 916985-21-2
    具有ATP竞争性 N
    形式 Tan solid
    Hill配方 C₂₂H₂₁N₃O₆S₂
    化学配方 C₂₂H₂₁N₃O₆S₂
    Molar Mass 487.6
    可逆 N
    结构配方图像
    生物信息
    主靶 Polo-like Kinase
    主靶IC50 126 nM against polo-like kinase 1
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,528282,Polo-like Kinase Inhibitor I

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