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描述 概述 Native, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds to fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain. 产品目录编号 528240 品牌系列 Calbiochem®
同义词 GPIIbIIIa, Fibrinogen Receptor, CD41/CD61 参考 参考 Schwarz M., et al. 2004. J. Pharmacol. Exp. Therap. 308, 1002.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.产品信息 形式 Liquid 配方 In 100 mM NaCl, 20 mM Tris-HCl, 1 mM CaCl₂, 50% glycerol, 0.1% TRITON® X-100 Detergent, ≤0.1% sodium azide, pH 7.4. 生物信息 来源 Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C). Avoid freeze/thaw cycles.
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