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merck millipore,默克密理博,527451,InSolution™ PKR Inhibitor - CAS 608512-97-6 - Calbiochem
产品名称：InSolution™ PKR Inhibitor - CAS 608512-97-6 - Calbiochem
产品型号：527451
The InSolution™ PKR Inhibitor, also referenced under CAS 608512-97-6, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation a More>>
merck millipore,默克密理博,527451,InSolution™ PKR Inhibitor - CAS 608512-97-6 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₃H₈N₄OS 608512-97-6 描述 概述 An imidazolo-oxindole compound that acts as a potent, ATP-binding site directed inhibitor of PKR. Shown to effectively inhibit RNA-induced PKR autophosphorylation (IC50 = 210 nM) and rescue PKR-dependent translation block (IC50 = 100 nM). The solid form of this compound (Cat. No. 527450) is also available. 产品目录编号 527451 品牌系列 Calbiochem®
同义词 C16, Double-stranded RNA-activated Protein Kinase Inhibitor I, Double-stranded RNA-dependent Protein Kinase Inhibitor I, EIF2AK2 Inhibitor I 参考 参考 Zhu, P.J., et al. 2011. Cell 147, 1384.
Jammi, N.V., et al. 2003. Biochem. Biophys. Res. Commun. 308, 50.产品信息 CAS号 608512-97-6 形式 Liquid 配方 A 50 mM (5 mg/373 µL) solution of PKR Inhibitor (Cat. No. 527450) in DMSO. Hill配方 C₁₃H₈N₄OS Molar Mass 268.3 吸湿 Hygroscopic
可逆 Y 结构配方图像 生物信息 主靶 PKR 纯度 ≥90% by HPLC 理化信息 细胞可渗透 Y 安全信息 R相 R: 36/38
Irritating to eyes and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Dry Ice Only
毒性 Irritant
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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