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描述 概述 Recombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Enhances the growth of both endothelial and hematopoietic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposis sarcoma cells, and a human erythroleukemic cell line, TF-1. 产品目录编号 496260 品牌系列 Calbiochem®
同义词 rhOSM 参考 参考 Boileau, C., et al. 2000. J. Immunol. 164, 5713.
Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.产品信息 CAS号 106956-32-5 形式 Lyophilized 配方 Lyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM. Molar Mass 22000 生物信息 生物活性 ED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1 纯度 ≥97% by SDS-PAGE 理化信息 污染物 Endotoxin: ≤1 EU/µg rhOSM 溶解度 Sterile PBS containing ≥ 0.1% BSA or HSA 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 ≤ -70°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
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