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merck millipore,默克密理博,482100,L-NIL, Dihydrochloride - Calbiochem
产品名称：L-NIL, Dihydrochloride - Calbiochem
产品型号：482100
A cell-permeable, potent and selective inhibitor of nitric oxide synthase that exhibits about 28-fold greater selectivity for inducible nitric oxide synthase than for the rat brain constitutive enzyme
merck millipore,默克密理博,482100,L-NIL, Dihydrochloride - Calbiochem
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重要规格表
经验配方 C₈H₁₇N₃O₂ · 2HCl 描述 概述 A cell-permeable, potent and selective inhibitor of nitric oxide synthase that exhibits about 28-fold greater selectivity for inducible nitric oxide synthase (IC50 = 3.3 µM) than for the rat brain constitutive enzyme (IC50 = 92 µM). Exhibits about 10-fold greater inhibitory potency than NG-Monomethyl-L-arginine (L-NMMA; Cat. No. 475886) in inhibiting γ-interferon-induced NO2- production (IC50 = 460 nM). 产品目录编号 482100 品牌系列 Calbiochem®
同义词 L-N⁶-(1-Iminoethyl)lysine, DiHCl 参考 参考 Moore, W.M., et al. 1996. J. Med. Chem. 39, 669.
Connor, J.R., et al. 1995. Eur. J. Pharmacol. 273, 15.
Stenger, S., et al. 1995. Eur. J. Pharmacol. 294, 703.
Moore, W.M., et al. 1994. J. Med. Chem. 37, 3886.
Stuehr, D.J., and Griffith, O.W. 1992. Adv. Enzymol. 65, 287.产品信息 具有ATP竞争性 N 形式 White solid Hill配方 C₈H₁₇N₃O₂ · 2HCl 化学配方 C₈H₁₇N₃O₂ · 2HCl Molar Mass 260.6 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 iNOS 主靶IC50 3.3 µM against inducible nitric oxide synthase 纯度 ≥98% by TLC 理化信息 细胞可渗透 Y 溶解度 H₂O 安全信息 R相 R: 36/37/38
Irritating to eyes, respiratory system and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for 3 months at 4°C.
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