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merck millipore,默克密理博,422706,KN-62 - CAS 127191-97-3 - Calbiochem
产品名称：KN-62 - CAS 127191-97-3 - Calbiochem
产品型号：422706
A cell-permeable, reversible, and selective inhibitor of CaM kinase II (Ki = 900 nM for rat brain CaM kinase II) that binds directly to the calmodulin binding site of the enzyme.
merck millipore,默克密理博,422706,KN-62 - CAS 127191-97-3 - Calbiochem
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重要规格表
经验配方 CAS号 C₃₈H₃₅N₅O₆S₂ 127191-97-3 描述 概述 A cell-permeable, reversible, and selective inhibitor of CaM kinase II (Ki = 900 nM for rat brain CaM kinase II) that binds directly to the calmodulin binding site of the enzyme. Also inhibits the growth of K562 cells in a dose-dependent manner. 产品目录编号 422706 品牌系列 Calbiochem®
同义词 1-[N,O-bis-(5-Isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine, P2X Antagonist II, Purinergic Receptor P2X Antagonist II 参考 参考 Minami, H., et al. 1994. Biochem. Biophys. Res. Commun. 199, 241.
Kato, M., et al. 1992. Neurosci. Lett. 129, 47.
Ishii, A., et al. 1991. Biochem. Biophys. Res. Commun. 176, 1051.
Ito, I., et al. 1991. Neurosci. Lett. 121, 119.
Tokumitsu, H., et al. 1990. J. Biol. Chem. 265, 4315.产品信息 CAS号 127191-97-3 具有ATP竞争性 N 形式 Off-white solid Hill配方 C₃₈H₃₅N₅O₆S₂ 化学配方 C₃₈H₃₅N₅O₆S₂ Molar Mass 721.9 可逆 Y 结构配方图像 生物信息 主靶 cam kinase 2 主靶Ki 900 nM for rat brain CaM kinase II 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.
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