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merck millipore,默克密理博,420133,JNK Inhibitor VI, TI-JIP153-163 - Calbiochem
产品名称：JNK Inhibitor VI, TI-JIP153-163 - Calbiochem
产品型号：420133
The JNK Inhibitor VI, TI-JIP153-163 controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
merck millipore,默克密理博,420133,JNK Inhibitor VI, TI-JIP153-163 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₆₁H₁₀₄N₂₀O₁₄ 描述 概述 A murine JIP-1 JNK-binding domain- (JBD) derived 11-mer peptide that directly interacts with JNK (KD in low µM range) and specifically inhibits JNK kinase activity without inhibitory effects towards ERK or p38. The inhibition is not limited only to JBD-containing substrates and is found to be mixed/non-competitive with respect to ATP. JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable, is also available (Cat. No. 420134). 产品目录编号 420133 品牌系列 Calbiochem®
同义词 H₂N-RPKRPTTLNLF-NH₂, Truncated Inhibitor based on JNK-Interacting Protein 1 参考 参考 Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.产品信息 具有ATP竞争性 N 形式 Lyophilized 配方 Supplied as a trifluoroacetate salt. Hill配方 C₆₁H₁₀₄N₂₀O₁₄ 化学配方 C₆₁H₁₀₄N₂₀O₁₄ Molar Mass 1341.6 吸湿 Hygroscopic
肽序列 H-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂ 可逆 N 生物信息 主靶 JNK 主靶IC50 KD in low µM range 纯度 ≥97% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO or H₂O 肽序列 H-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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