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品种反应性 主要应用 宿主 格式 抗体类型 Rb, B, H, M, Po, R EA Rb Purified Polyclonal Antibody 描述 产品目录编号 36-006 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-CPI-17 (Thr38) Antibody 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%. 应用 应用 Detect phospho-CPI-17 (Thr38) using this Anti-phospho-CPI-17 (Thr38) Antibody validated for use in EA. 主要应用 - Enzyme Assay
生物信息 免疫原品种 Peptide corresponding to amino acids 35-46 of human CPI-17. 宿主 Rabbit 特异性 CPI-17 phosphorylated on Threonine 38. 同种型 IgG 品种反应性 RabbitBovineHumanMousePigRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_033256.1
Entrez基因汇总 PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration.[supplied by OMIM] 基因符号 - PPP1INL
- PPP1R14A
- 17-KDasprotein
- CPI-17
- CPI17
修改 - Phosphorylation
纯化方法 Protein A purfied UniProt编号 - Q96A00
UniProt汇总 FUNCTION: SwissProt: Q96A00 # Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
SIZE: 147 amino acids; 16693 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
SIMILARITY: SwissProt: Q96A00 ## Belongs to the PP1 inhibitor family.产品使用声明 质量保证 Routinely evaluated by immunoblot on phosphorylated recombinant CPI-17. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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