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merck millipore,默克密理博,382175,Histone Deacetylase Inhibitor VIII - CAS 1045792-66-2 - Calbiochem
产品名称:Histone Deacetylase Inhibitor VIII - CAS 1045792-66-2 - Calbiochem
产品型号:382175
The Histone Deacetylase Inhibitor VIII, also referenced under CAS 1045792-66-2, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Struct More>>
merck millipore,默克密理博,382175,Histone Deacetylase Inhibitor VIII - CAS 1045792-66-2 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₂H₃₀N₄O₆ 1045792-66-2 描述 概述 A cell-permeable, active site Zn2+-targeting phenylisoxazolo-hydroxamate that acts a potent and highly selective HDAC6 inhibitor (IC50 = 0.002, 0.42, 90.7, 252, 271 and 6851 nM against HDAC-6, -3, -10, -2, -1 and -8, respectively). Shown to be more potent than SAHA in inhibiting the proliferation of a panel of pancreatic cancer cell lines (IC50 <1.0 µM). 产品目录编号 382175 品牌系列 Calbiochem®
同义词 N-(4-(3-(((7-Hydroxyamino-7-oxoheptyl)amino)carbonyl)-5-isoxazolyl)phenyl)-1,1-dimethylethylester, carbamic acid, HDAC Inhibitor VIII 参考 参考 Kozikowski, A.P., et al. 2008. J. Med. Chem. 51, 4370. 产品信息 CAS号 1045792-66-2 形式 Beige to light brown solid Hill配方 C₂₂H₃₀N₄O₆ 化学配方 C₂₂H₃₀N₄O₆ Molar Mass 446.5 生物信息 纯度 ≥95% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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