merck millipore,默克密理愽
  • merck millipore,默克密理博,382111,Histone Acetyltransferase Inhibitor IV, CPTH2 - CAS 357649-93-5 - Calbiochem

  • merck millipore,默克密理博,382111,Histone Acetyltransferase Inhibitor IV, CPTH2 - CAS 357649-93-5 - Calbiochem

    产品名称：Histone Acetyltransferase Inhibitor IV, CPTH2 - CAS 357649-93-5 - Calbiochem
    产品型号：382111


    merck millipore,默克密理博,382111,Histone Acetyltransferase Inhibitor IV, CPTH2 - CAS 357649-93-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,382111,Histone Acetyltransferase Inhibitor IV, CPTH2 - CAS 357649-93-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₁₄ClN₃S357649-93-5
    描述
    概述 A cell-permeable thiazolyl-hydrazone compound that inhibits the acetylation of histone H3 by recombinant human Gcn5 in a substrate-competive manner, while exhibiting little activity against rhGcn5 autoacetylation. Although functional knockout of Gcn5 in Saccharomyces cerevisiae by genetic deletion or by CPTH2 treatment is not detrimental to the survival of the budding yeast, CPTH2 treatment is shown to inhibit the growth of yeast strain genetically deleted of Gcn5, but not strains deleted of Elp3 or Sas2.
    产品目录编号 382111
    品牌系列 Calbiochem®
    同义词 HAT Inhibitor IV, Cyclopentylidene-(4-(4ʹ-chlorophenyl)thiazol-2-yl)hydrazone, GCN5 Inhibitor II, N-acetyltransferase 10 Inhibitor I, NAT10 Inhibitor I
    参考
    参考 Larrieu, D., et al. 2014. Science, 344, 527.
    Chimenti, F., et al. 2009. J. Med. Chem. 52, 530.
    产品信息
    CAS号 357649-93-5
    形式 Brown solid
    Hill配方 C₁₄H₁₄ClN₃S
    化学配方 C₁₄H₁₄ClN₃S
    Molar Mass 291.8
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,382111,Histone Acetyltransferase Inhibitor IV, CPTH2 - CAS 357649-93-5 - Calbiochem

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