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描述 概述 Native, human eosinophil peroxidase. Eosinophil peroxidase is a secreted hemoprotein that catalyzes oxidations of various substrates by hydrogen peroxide. Together with other leukocyte-derived enzymes, such as Myeloperoxidase (Cat. No. 475911), EPO plays an important role in the pathogenesis of asthma by mediating oxidative events that lead to the production of ROS (reactive oxygen species) and RNS (reactive nitrogen species). 产品目录编号 374096 品牌系列 Calbiochem®
同义词 EPO 参考 参考 Andreadis., et al. 2003. Free Radic. Biol. Med. 35, 213.
Borelli, V., et al. 2003. Infect. Immun. 71, 605.
Erpenbeck, V.J., et al. 2003. Clin. Exp. Allergy 33, 331.
McElhinney, B., et al. 2003. J. Leukoc. Biol. 74, 897.
Aldridge, R.E., et al. 2002. Free Radic. Biol. Med. 33, 847.
Kettle, A.J., and Winterbourn, C.C. 1988. Biochim. Biophys. Acta 957, 185.
Desser, R.K., et al. 1972. Arch. Biochem. Biophys. 148, 452.
Hager, L.P., et al. 1966. J. Biol. Chem. 241, 1769.产品信息 CAS号 9003-99-0 EC号 1.11.1.7 形式 Lyophilized 配方 Lyophilized from 5 mM phosphate buffer, pH 7.0. Molar Mass 70500 生物信息 纯度 ≥90% by SDS-PAGE 来源 Prepared from tissue that has been shown by certified tests to be negative for HBsAg and for antibodies to HCV and HIV. 特异活性 ≥ 270 units/mg protein (Guaiacol Assay Method) 储存和货运信息 货运代码 Shipped with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution refrigerate (4°C). If solutions must be frozen the protein concentration should be >1 mg/ml and the activity determined following each thaw.
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