merck millipore,默克密理愽
  • merck millipore,默克密理博,361568,GSK-3β Inhibitor XXV - Calbiochem

  • merck millipore,默克密理博,361568,GSK-3β Inhibitor XXV - Calbiochem

    产品名称：GSK-3β Inhibitor XXV - Calbiochem
    产品型号：361568
    The GSK-3β Inhibitor XXV controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,361568,GSK-3β Inhibitor XXV - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,361568,GSK-3β Inhibitor XXV - Calbiochem

    重要规格表

    经验配方
    C₁₅H₁₁ClN₄O₃
    描述
    概述 A blood brain barrier permeable oxadiazole compound that acts as a potent, reversible and ATP-competitive inhibitor of GSK-3β activity (IC50 = 17.1 nM) with excellent selectivity over Cdk2 (22% inhibition at 10 µM). Shown to elevate liver glycogen levels by ~3.5- and ~4.3-fold in C57BL/6N mice when dosed at 5 and 15 mg/kg (i.p.) amounts.
    产品目录编号 361568
    品牌系列 Calbiochem®
    同义词 5-(4-Nitrophenyl)-N-(3-chloro-4-methyl)phenyl-1,3,4-oxadiazol-2-amine, N-(3-Chloro-4-methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol-2-amine, M SEW00923SC
    参考
    参考 Khanfar, M.A., et al. 2010. J. Med. Chem. 53, 8534.
    产品信息
    形式 Yellow solid
    Hill配方 C₁₅H₁₁ClN₄O₃
    化学配方 C₁₅H₁₁ClN₄O₃
    Molar Mass 330.7
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,361568,GSK-3β Inhibitor XXV - Calbiochem

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