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merck millipore,默克密理博,344280,Fostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem
产品名称：Fostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem
产品型号：344280
An antitumor antibiotic that acts as a potent protein phosphatase 2A (PP2A) inhibitor (IC₅₀ = 3.2 nM).
merck millipore,默克密理博,344280,Fostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,344280,Fostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem
重要规格表
经验配方 CAS号 C₁₉H₂₆O₉PNa 87860-39-7 描述 概述 An antitumor antibiotic that acts as a potent protein phosphatase 2A (PP2A) inhibitor (IC50 = 3.2 nM). Inhibits protein phosphatase 1 (PP1) at much higher concentrations (IC50 = 131 µM). Does not affect the activity of protein phosphatase 2B (PP2B). Inhibits the catalytic activity of DNA topoisomerase II (topo II) and arrests cell growth at the G2/M phase of the cell cycle in a dose-dependent manner. 产品目录编号 344280 品牌系列 Calbiochem®
同义词 FST, Phosphotrienin 参考 参考 Cheng, A., et al. 1998. Cancer Res. 58, 3611.
Walsh, A.H., et al. 1997. FEBS Lett. 416, 230.
Boritzki, T.J., et al. 1988. Biochem. Pharmacol. 37, 4063.产品信息 CAS号 87860-39-7 具有ATP竞争性 N 形式 Colorless solid Hill配方 C₁₉H₂₆O₉PNa 化学配方 C₁₉H₂₆O₉PNa Molar Mass 452.4 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 PP2a 主靶IC50 3.2 nM, 131 µM, against protein phosphatase 2A (PP2A), protein phosphatase 1 (PP1), respectively 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 EtOH, MeOH, or H₂O GHS安全信息 RTECS UQ0600000 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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