• merck millipore,默克密理博,323115,DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem
  • merck millipore,默克密理博,323115,DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem

    产品名称:DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem
    产品型号:323115
    The DNA Repair Pathway Inhibitor, NS-123, also referenced under CAS 101860-83-7, modulates DNA Repair Pathway. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,323115,DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,323115,DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉H₈BrNO₃101860-83-7
    描述
    概述 A cell-permeable nitro-propiophenone compound that preferentially enhances tumor growth-inhibitory effects of ionizing radiation (~ 5 µM in U251, HT-29 and A549 tumor cells and in U251 xenograft mouse model, 50 mg/kg, i.p.) with no apparent effect on normal human glial cells, Zebrafish embryos and nude mice. Shown to increase the accumulation of unrepaired double-strand DNA breaks and prolong the damage-dependent signaling.
    产品目录编号 323115
    品牌系列 Calbiochem®
    同义词 4ʹ-Bromo-3ʹ-nitropropiophenone, Radiation Sensitizer, NS-123
    参考
    参考 Lally, B.E., et al. 2007. Cancer Res. 67, 8791.
    产品信息
    CAS号 101860-83-7
    形式 Off-white solid
    Hill配方 C₉H₈BrNO₃
    化学配方 C₉H₈BrNO₃
    Molar Mass 258.1
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    安全信息
    S相 S: 22-24/25

    Do not breathe dust.
    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,323115,DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem

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