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merck millipore,默克密理博,323115,DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem
产品名称:DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem
产品型号:323115
The DNA Repair Pathway Inhibitor, NS-123, also referenced under CAS 101860-83-7, modulates DNA Repair Pathway. This small molecule/inhibitor is primarily used for Cell Structure applications.
merck millipore,默克密理博,323115,DNA Repair Pathway Inhibitor, NS-123 - CAS 101860-83-7 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₉H₈BrNO₃ 101860-83-7 描述 概述 A cell-permeable nitro-propiophenone compound that preferentially enhances tumor growth-inhibitory effects of ionizing radiation (~ 5 µM in U251, HT-29 and A549 tumor cells and in U251 xenograft mouse model, 50 mg/kg, i.p.) with no apparent effect on normal human glial cells, Zebrafish embryos and nude mice. Shown to increase the accumulation of unrepaired double-strand DNA breaks and prolong the damage-dependent signaling. 产品目录编号 323115 品牌系列 Calbiochem®
同义词 4ʹ-Bromo-3ʹ-nitropropiophenone, Radiation Sensitizer, NS-123 参考 参考 Lally, B.E., et al. 2007. Cancer Res. 67, 8791. 产品信息 CAS号 101860-83-7 形式 Off-white solid Hill配方 C₉H₈BrNO₃ 化学配方 C₉H₈BrNO₃ Molar Mass 258.1 结构配方图像 生物信息 纯度 ≥98% by HPLC 理化信息 溶解度 DMSO or EtOH 安全信息 S相 S: 22-24/25
Do not breathe dust.
Avoid contact with skin and eyes.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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