merck millipore,默克密理愽
  • merck millipore,默克密理博,239824,CXCR7 Agonist, VUF11207 - Calbiochem

  • merck millipore,默克密理博,239824,CXCR7 Agonist, VUF11207 - Calbiochem

    产品名称：CXCR7 Agonist, VUF11207 - Calbiochem
    产品型号：239824
    The CXCR7 Agonist, VUF11207 controls the biological activity of CXCR7. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,239824,CXCR7 Agonist, VUF11207 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,239824,CXCR7 Agonist, VUF11207 - Calbiochem

    重要规格表

    经验配方
    C₂₇H₃₅FN₂O₄
    描述
    概述 A styrene-amide derivative that acts as a high affinity and high potency ligand of CXCR7 chemokine receptor (pKi = 8.1) and induces the recruitment of β-arrestin2 and subsequent interenalization of CXCR7. Exposure of HEK293 T cells transiently transfected with cDNA encoding both CXCR7-RLuc and β-arrestin 2-YFP to VUF11207 is shown to induce a dose-dependent increase in bioluminescence resonance energy transfer (BRET) signal (EC50 = 1.6 nM) indicating its agonist role in β-arrestin2 is recruited to the active receptor.
    产品目录编号 239824
    品牌系列 Calbiochem®
    同义词 RDC-1 Agonist, GPR159 Agonist, (E)-N-(3-(2-fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)benzamide, RDC1 agonist, CMKOR1 Agonist, CXCR-7 Agonist, CXC-R7 Agonist
    参考
    参考 Wijtmans, M., et al. 2011, Eur J Med Chem 51, 184.
    产品信息
    形式 Light yellow oil
    Hill配方 C₂₇H₃₅FN₂O₄
    Molar Mass 470.6
    可逆 Y
    结构配方图像
    生物信息
    主靶 CXCR7
    纯度 ≥99% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,239824,CXCR7 Agonist, VUF11207 - Calbiochem

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