merck millipore,默克密理愽

  • 产品介绍

  • 重要规格表

    主要应用 品种 级联部件
    EAHumanSubstrate
    描述
    产品目录编号 23-039
    品牌系列 Upstate
    商名
    • Upstate
    描述 Smad7
    长描述 N-terminal c-Myc, 6His-tagged, recombinant human Smad7 full length, expressed by baculovirus in Sf21 insect cells.
    Alternate Names
    • Mothers against decapentaplegic homologue 7, MAD homologue 7, Mothers against DPP homologue 7, Mothers against decapentaplegic homologue 8, MADH7, MADH8
    背景信息 The TGF-β signalling cascade regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, adhesion and migration. It plays a fundamental role in a number of different physiological and pathological processes, such as embryonic development, adult homoeostasis, tumourigenesis and tissue fibrogenesis. Smad7 has been identified as a key negative regulator of TGF-β signalling, antagonising it through multiple mechanisms in both the cytoplasm and in the nucleus. Altered expression of Smad7 is often associated with human diseases, such as cancer, tissue fibrosis and inflammatory diseases.
    应用
    主要应用
    • Enzyme Assay
    生物信息
    品种 Human
    级联部件 Substrate
    Entrez基因编号
    • NM_005904
    纯化方法 Purified using immobilized metal affinity chromatography.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 10 µg


上一件merck millipore产品：merck millipore,默克密理博,16-234,Anti-FAK Antibody, clone 4.47, Alexa Fluor 555 conjugate
下一件merck millipore产品：merck millipore,默克密理博,HTS133RTA,Ready-to-Assay™ TSH Glycoprotein Hormone Receptor Frozen Cells


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