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经验配方 CAS号 C₁₇H₁₆O₄ 104594-70-9 描述 概述 A cell-permeable active component of propolis from honeybee hives. Known to have antiviral, anti-inflammatory, and immunomodulatory properties. Has also recently been shown to act as a potent and specific inhibitor of NF-κB activation. An inhibitor of HIV-1 integrase activity. Inhibits the growth of different types of transformed cells. Has been reported to suppress lipid peroxidation. Inhibits ornithine decarboxylase, protein tyrosine kinase (PTK), and lipoxygenase activities. Also induces apoptosis in cloned rat embryo fibroblast (CREF) cells transformed by a number of different oncogenes. 产品目录编号 211200 品牌系列 Calbiochem®
同义词 Caffeic Acid Phenethyl Ester, Synthetic 参考 参考 Nicklaus, M.C., et al. 1997. J. Med. Chem. 40, 920.
Natarajan, K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 9090.
Burke, T.R., Jr., et al. 1995. J. Med. Chem. 38, 4171.
Laranjinha, J., et al. 1995. Arch. Biochem. Biophys. 323, 373.
Su, Z.-Z., et al. 1995. Anticancer Res. 15, 1841.
Zheng, Z.S., et al. 1995. Oncol. Res. 7, 445.
Su, Z.-Z., et al. 1994. Cancer Res. 54, 1865.
Fesen, M.R., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2399.
Guarini, L., et al. 1992. Cell. Mol. Biol. 38, 513.产品信息 CAS号 104594-70-9 具有ATP竞争性 N 形式 White to off-white solid Hill配方 C₁₇H₁₆O₄ 化学配方 C₁₇H₁₆O₄ Molar Mass 284.3 可逆 N 结构配方图像 生物信息 主靶 HIV-integrase 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or EtOH 安全信息 R相 R: 36/37/38
Irritating to eyes, respiratory system and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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