merck millipore,默克密理愽
  • merck millipore,默克密理博,200487,β-Amyloid Oligomer Inhibitor, K01-162 - Calbiochem

  • merck millipore,默克密理博,200487,β-Amyloid Oligomer Inhibitor, K01-162 - Calbiochem

    产品名称：β-Amyloid Oligomer Inhibitor, K01-162 - Calbiochem
    产品型号：200487
    The β-Amyloid Oligomer Inhibitor, K01-162 controls the biological activity of β-Amyloid Oligomer.

    merck millipore,默克密理博,200487,β-Amyloid Oligomer Inhibitor, K01-162 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,200487,β-Amyloid Oligomer Inhibitor, K01-162 - Calbiochem

    重要规格表

    经验配方
    C₁₅H₁₄BrN
    描述
    概述 A cell permeable, fluorene compound that destabilizes the aggregation state of β-amyloid oligomers (AβO) by directly targeting AβO and inhibiting AβO binding to synapses. It displays full MC65 protection at 125 nM, with an EC50 of 80 nM in a neuronal MC65 culture-based assay, and substantially reduces intraneuronal AβO in primary neuronal culture at concentrations between 100 nM and 10 µM. Furthermore, it is shown to significantly reduce amyloid levels by 50% compared with control in vivo in a 5xFAD mice cerebral Aβ amyloidosis model when dosed intracerebroventricularly without apparent toxicity.
    产品目录编号 200487
    品牌系列 Calbiochem®
    同义词 AβO Inhibitor, K01-162
    参考
    参考 Hong, H-S., et al. 2010. Neurobiol. Aging 31, 1690.
    产品信息
    形式 Colorless syrup
    Hill配方 C₁₅H₁₄BrN
    化学配方 C₁₅H₁₄BrN
    Molar Mass 288.18
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,200487,β-Amyloid Oligomer Inhibitor, K01-162 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,MAB846,Anti-Mumps Blend Antibody, fusion protein, clones 570-7A, 570-12G


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