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经验配方 CAS号 C₂₆H₃₈N₈O₇ 137813-35-5 描述 概述 Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation. 产品目录编号 182015 品牌系列 Calbiochem®
同义词 RGDFV Peptide, Cyclic 参考 参考 Shono, T., et al. 2001. Exp. Cell Res. 268, 169.
Matsuno, H., et al. 1994. Circulation 90, 2203.
Noiri, E., et al. 1994. Kidney Int. 46, 1050.
Gurrath, M., et al. 1992. Eur. J. Biochem. 210, 911.产品信息 CAS号 137813-35-5 具有ATP竞争性 N 形式 White solid 配方 Supplied as a trifluoroacetate salt Hill配方 C₂₆H₃₈N₈O₇ 化学配方 C₂₆H₃₈N₈O₇ Molar Mass 574.6 吸湿 Hygroscopic
可逆 N 生物信息 主靶 inhibits tumor cell adhesion to laminin and vitronectin substrates 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 1N Acetic Acid 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
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