merck millipore,默克密理愽
  • merck millipore,默克密理博,171262,AMPK Activator V, Ampkinone - Calbiochem

  • merck millipore,默克密理博,171262,AMPK Activator V, Ampkinone - Calbiochem

    产品名称：AMPK Activator V, Ampkinone - Calbiochem
    产品型号：171262
    The AMPK Activator V, Ampkinone modulates the biological activity of AMPK. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,171262,AMPK Activator V, Ampkinone - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,171262,AMPK Activator V, Ampkinone - Calbiochem

    重要规格表

    经验配方
    C₃₁H₂₃NO₆
    描述
    概述 A cell-permeable benzopyran compound that stimulates both LKB1 and CaMKK-mediated AMPK activity indirectly with no noticeable effect on purified AMPK, cellular AMP/ATP ratio, PI 3-K/Akt signaling and respiratory chain, and displays antidiabetic and antiobesity properties. Shown to induce phosphorylation of AMPK-Thr172 and ACC-Ser79 in L6 cells (EC50 = 4.3 µM), C2C12 myocytes, 3T3-L1 preadipocytes and HepG2 hepatic cells, and enhance glucose uptake and insulin sensitivity in high fat-diet-induced obesity mouse model (10 mg/kg, s.c.) with the lowering of cholesterol and nonesterified fatty acids.
    产品目录编号 171262
    品牌系列 Calbiochem®
    同义词 AKN, AMPK Signaling Activator V
    参考
    参考 Oh, S., et al. 2010. J. Med. Chem. 53, 7405.
    产品信息
    形式 Yellow powder
    Hill配方 C₃₁H₂₃NO₆
    化学配方 C₃₁H₂₃NO₆
    Molar Mass 505.5
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,171262,AMPK Activator V, Ampkinone - Calbiochem

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