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描述 产品目录编号 14-350 品牌系列 Upstate
商名 - Upstate
描述 PTPβ Protein, 10000 units 概述 GST-tagged, full-length intracellular domain of human PTPβ 应用 应用 GST-tagged, full-length intracellular domain of human PTPβ, for use in Phosphatase Assays. 主要应用 - Phosphatase Assay
生物信息 来源 expressed in E. coli 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_002837.2
Entrez基因汇总 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Two transcript variants encoding different isoforms have been found for this gene. 基因符号 - FLJ44133
- PTPRB
- R-PTP-beta
- HPTP-BETA
- PTPB
- R-PTP-BETA
- MGC59935
- HPTPB
- DKFZp686E2262
- MGC142023
- DKFZp686H15164
蛋白靶 PTPβ 纯化方法 Purified from E. coli lysate using glutathioneagarose beads 靶子系列 Tyr phosphatase UniProt编号 - P23467
UniProt汇总 SIZE: 1997 amino acids; 224268 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P23467 ## Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily. & Contains 17 fibronectin type-III domains. & Contains 1 tyrosine-protein phosphatase domain.产品使用声明 质量保证 routinely evaluated by dephosphorylation of p-nitrophenyl phosphate (pNPP) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -20C 包装信息 数量 10000 units
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