merck millipore,默克密理愽
  • merck millipore,默克密理博,14-249M,p38δ/SAPK4 Protein, active, 250 µg

  • merck millipore,默克密理博,14-249M,p38δ/SAPK4 Protein, active, 250 µg

    产品名称：p38δ/SAPK4 Protein, active, 250 µg
    产品型号：14-249M
    Active, recombinant GST fusion protein fused to full length human p38δ/SAPK4, for use in Kinase Assays.

    merck millipore,默克密理博,14-249M,p38δ/SAPK4 Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-249M,p38δ/SAPK4 Protein, active, 250 µg

    描述
    产品目录编号 14-249M
    品牌系列 Upstate
    商名
    • Upstate
    描述 p38δ/SAPK4 Protein, active, 250 µg
    概述 Recombinant GST fusion protein fused to full length human p38δ/SAPK4

    CHK3
    应用
    应用 Active, recombinant GST fusion protein fused to full length human p38δ/SAPK4, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed in E. coli
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_002754.3
    Entrez基因汇总 The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
    基因符号
    • p38delta
    • MAPK13
    • MGC99536
    • PRKM13
    • SAPK4
    蛋白靶 p38δ/SAPK4
    纯化方法 Affinity chromatography on glutathione Sepharose™ beads after activation with SKK3/MEK6
    靶子系列 CMGC
    UniProt编号
    • O15264
    UniProt汇总 FUNCTION: SwissProt: O15264 # Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating downstream targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K.
    COFACTOR: Magnesium.
    SIZE: 365 amino acids; 42090 Da
    TISSUE SPECIFICITY: Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells.
    DOMAIN: SwissProt: O15264 The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
    PTM: Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.
    SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of MBP in vitro
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -20°C
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-249) and in bulk (cat# 14-249-K).

    merck millipore,默克密理博,14-249M,p38δ/SAPK4 Protein, active, 250 µg

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下一件merck millipore产品：merck millipore,默克密理博,33-054,PIP4-Kinase HTRF Assay


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