merck millipore,默克密理愽
  • merck millipore,默克密理博,124009,Akt Inhibitor III - Calbiochem

  • merck millipore,默克密理博,124009,Akt Inhibitor III - Calbiochem

    产品名称：Akt Inhibitor III - Calbiochem
    产品型号：124009
    The Akt Inhibitor III controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,124009,Akt Inhibitor III - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,124009,Akt Inhibitor III - Calbiochem

    重要规格表

    经验配方
    C₂₈H₅₇O₉P
    描述
    概述 A cell permeable, reversible, and substrate competitive phosphatidylinositol analog that inhibits the activation of Akt and select downstream substrates without decreasing phosphorylation of PDK-1 or other kinases downstream of Ras, such as MAPK. Also acts as a potent inducer of apoptosis and selectively kills a variety of cancer cell lines that contain high levels of active Akt. When used at a concentration of 10 µM, it is reported to activate p38α/SAPK2α MAP kinase. At 10 µM it will also inhibit PKA activity.
    产品目录编号 124009
    品牌系列 Calbiochem®
    同义词 SH-6
    参考
    参考 Gills, J.J., et al. 2007. J. Biol. Chem. in press.
    Kozikowski, A.P., et al. 2003. J. Am. Chem. Soc.125, 1144.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₈H₅₇O₉P
    化学配方 C₂₈H₅₇O₉P
    Molar Mass 568.7
    可逆 Y
    结构配方图像
    生物信息
    主靶 Akt
    纯度 ≥98% by NMR
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,124009,Akt Inhibitor III - Calbiochem

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