merck millipore,默克密理博,07-833,Anti-phospho-Gab1 (Tyr627) Antibody

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merck millipore,默克密理博,07-833,Anti-phospho-Gab1 (Tyr627) Antibody
产品名称：Anti-phospho-Gab1 (Tyr627) Antibody
产品型号：07-833
This Anti-phospho-Gab1 (Tyr627) Antibody is validated for use in WB for the detection of phospho-Gab1 (Tyr627).

merck millipore,默克密理博,07-833,Anti-phospho-Gab1 (Tyr627) Antibody

产品介绍

merck millipore,默克密理博,07-833,Anti-phospho-Gab1 (Tyr627) Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	07-833
品牌系列	Upstate
商名	Upstate
描述	Anti-phospho-Gab1 (Tyr627) Antibody
Alternate Names	GAB1, GRB2-associated binding protein 1 GAB1

产品信息
格式	Affinity Purified
演示	100 μL of affinity purified rabbit polyclonal IgG in 50% storage buffer (PBS (without Mg²⁺ and Ca²⁺), pH 7.3 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide) and 50% glycerol.

应用
应用	This Anti-phospho-Gab1 (Tyr627) Antibody is validated for use in WB for the detection of phospho-Gab1 (Tyr627).
主要应用	Western Blotting
应用说明	Immunoblot Analysis: 1:1000 dilutions of this lot detected phospho-Gab1 (Tyr627) in RIPA lysate of PDGF treated NIH3T3 cells.

生物信息
免疫原品种	Peptide corresponding to amino acid region encompassing the human and mouse phospho-Gab1 (Tyr627)
宿主	Rabbit
特异性	Gab1 phosphorylated on Tyrosine residue 627.
同种型	IgG
品种反应性	Mouse
Species Reactivity Note	Predicted to cross-react with human based on 100% sequence homology, but have not been tested.
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_207123.1 NM_002039.2
Entrez基因汇总	The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. The encoded protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
基因符号	GAB1
修改	Phosphorylation
纯化方法	Affinity Purfied
UniProt编号	Q13480
UniProt汇总	FUNCTION: SwissProt: Q13480 # Probably involved in EGF and insulin receptor signaling. SIZE: 694 amino acids; 76616 Da SUBUNIT: Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2. PTM: Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains. SIMILARITY: SwissProt: Q13480 ## Belongs to the GAB family. & Contains 1 PH domain.

产品使用声明
质量保证	Routinely evaluated by immunoblot.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.