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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-723 品牌系列 Upstate
商名 - Upstate
描述 Anti-Apobec3 Antibody, NT 产品信息 格式 Affinity Purified 演示 Affinity purified antibody in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4. 应用 应用 Anti-Apobec3 Antibody, NT is a high quality Rabbit Polyclonal Antibody for the detection of Apobec3 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated, synthetic peptide corresponding to amino acids 82-95 (C-DKVLKVLSPREEFK) of mouse apolipoprotein B editing complex 3 (Apobec3), with an N-terminal cysteine added for conjugation purposes. 宿主 Rabbit 特异性 Apobec3 同种型 IgG 品种反应性 Mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_145298.5
- NM_001006666.1
Entrez基因汇总 This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. 基因符号 - ARP8
- APOBEC3F
- MGC74891
- KA6
- BK150C2.4.MRNA
纯化方法 Immunoaffinity purified UniProt编号 - Q8IUX4
UniProt汇总 FUNCTION: SwissProt: Q8IUX4 # After being packaged into HIV-1 virions, blocks productive infection by massively editing dC residues to dU on the DNA minus strand during reverse transcription. The editing of the minus strand DNA of HIV-1 during reverse transcription leads to G- to-A transitions in the plus strand. The inhibition of viral replication is either due to the degradation of the minus strand before its integration or to the lethality of the hypermutations.
COFACTOR: Zinc (By similarity).
SIZE: 373 amino acids; 45020 Da
SUBUNIT: Forms heterodimers with APOBEC3G. Binds HIV-1 Vif. In the absence of Vif protein, specifically packaged into HIV-1 virions.
TISSUE SPECIFICITY: Widely expressed, including in lymphoid tissues, such as thymus and peripheral blood leukocytes. No expression detected in permissive lymphoid.
SIMILARITY: SwissProt: Q8IUX4 ## Belongs to the cytidine and deoxycytidylate deaminase family.
MISCELLANEOUS: It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at 2 to 8°C from date of shipment. 包装信息 数量 100 µL
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