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品种反应性 主要应用 宿主 格式 抗体类型 H IP, IH(P) Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-2070-I Replaces 07-2070 描述 Anti-PRDM9 Antibody Alternate Names - PR domain-containing protein 9
- Histone-lysine N-methyltransferase PRDM9
- PR domain zinc finger protein 9
背景信息 Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Like other PR-domain-containing proteins, PRDM9 (also known as MEISETZ, or Meiosis-induced factor containing PR/SET domain and zinc-finger motif) is thought to be involved in transcriptional regulation. PRDM9/MEISETZ is a novel histone tri-methyltransferase that regulates meiosis-specific epigenesis. PRDM9/MEISETZ catalyses H3K4 trimethylation and activates transcription through its methylation activity. It contains a KRAB motif also found in SSX genes. 产品信息 格式 Affinity Purified 控制 - Human seminiferous tubules tissue
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect PRDM9 using this rabbit polyclonal antibody, Anti-PRDM9 Antibody validated for use in IHC (Paraffin) & IP. 主要应用 - Immunoprecipitation
- Immunohistochemistry (Paraffin)
应用说明 Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected PRDM9 in human pancreas tissue.
Immunoprecipitation Analysis: A representative lot immunoprecipitated 10 µg of PRDM9 from human testis tissue lysate.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human PRDM9. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_064612
基因符号 - PFM6
- PRDM9
纯化方法 Affinity purified UniProt编号 - Q9NQV7
产品使用声明 质量保证 Evaluated by Immunohistochemistry in human seminiferous tubules tissue.
Imunnohistochemistry Analysis: A 1:200 dilution of this antibody detected PRDM9 in human seminiferous tubules tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 200 µg
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